Depending on the application future GNSS navigation receiver performance may be affected by quite different interference sources. While for aeronautical applications, the terrestrial radio navigation system (DME/TACAN) and a military communication system (JTIDS) may represent the major interference source, navigation receivers utilising signals on E6, are expected to be mainly affected by pulsed interference caused by L-band radar. Terrestrial mobile applications, such as indoor navigation, operating in environments, characterised by severe shadowing, the navigation performance will most likely suffer from intra-system interference due to substantially different signal power levels being received from the different satellites. As a consequence, efficient interference mitigation for the different application areas will require techniques well adapted to the characteristics of the relevant interference sources being anticipated. In order to counteract pulsed interference due to DME/TACAN, JTIDS or pulsed L-band radar, the pulse blanking at RF-front end as well as digital signal processing level of a navigation receiver has been already extensively studied. For efficient intra-system interference mitigation, the adoption of approaches, well known from communications (“interference cancellation”), may lead to appropriate mitigation performance.